For example, patients with FoH tend to show avoidance behaviors, including cutting the dose of insulin, overeating, and reducing physical activity, etc. As shown in several studies, the relationship between anxiety and FoH was significant (Gonder-Frederick et al., 2006; Anderbro et al., 2015; Rechenberg et al., 2017; Castellano-Guerrero et al., 2018), and a study regarded FoH as one of the anxiety-related syndromes associated with diabetes (Majidi et al., 2015). Here, INS is linked to Anxiety.