T, SHBG, and FAI were negatively correlated (−0.13, −0.10, and −0.11, respectively) (P < 0.05), while acne, hirsutism, fasting insulin, and HOMA-IR were positively correlated (0.079, 0.11, 0.084, and 0.082, respectively) (P < 0.05). This evidence concerns the gene INS and acne.