In a study of a family with inherited generalized epilepsy and coexistent paroxysmal dyskinesia (GEPD), a heterozygous A-G transition in exon 10 of KCNMA1 was identified, which results in the D434G mutation in the BK channel subunit Slo1 (Du et al., 2005; Figure 3A). The gene discussed is KCNMA1; the disease is generalized epilepsy.