Very recently, utilizing I-TASSER structure prediction and 3-D active site modeling, Liu et al. identified the first CTRP9 C-terminal polypeptide (CTRP9-281), which exerts superior cardioprotective actions after myocardial infarction in vivo (Liu et al., 2021). Here, C1QTNF9 is linked to myocardial infarction.