Because chemokines and especially CXCL12 can facilitate decisive crosstalk between B and T cells, notably by recruiting these immune cells in lymphoid and non-lymphoid tissues and organs (Minami et al., 2017), the CXCL12/CXCR4 axis received particular attention in autoimmunity (Karin, 2010; Janssens et al., 2018). Here, CXCL12 is linked to Autoimmunity.