Figures 1A,B shows differential expression of LDH-A and LDH-B mRNA in various breast cancer cell lines; LDH-A was expressed in both ER +ve (MCF7 and YS1.2) and ER −ve lines (MDA-MB-231, pII and YS2.5), while LDH-B was specifically expressed only in ER −ve cells. This evidence concerns the gene LDHA and breast carcinoma.