As circulating immune cells, including monocytes, migrate into sites of inflammation during the inflammatory response and CCL2 is the key chemoattractant orchestrating migration (Deshmane et al., 2009), our results, along with previous findings, imply that miconazole mediates its therapeutic effects, apart from its antifungal efficacy, by suppressing the inflammation induced by DAMPs which can be released from damaged cells after fungal infections. The gene discussed is CCL2; the disease is fungal infectious disease.