For instance, sustained brain delivery of VEGF via injectable hydrogels was protective against quinolinic acid-induced neurodegeneration (Emerich et al., 2010), and low VEGF levels have been associated to another debilitating neurological disorder, spinocerebellar ataxia type 1 (Cvetanovic et al., 2011). The gene discussed is VEGFA; the disease is spinocerebellar ataxia type 1.