PYY and Anorexia: Interestingly, although acute oral propionate administration (in the form of inulin-propionate ester) in overweight adults also suppressed energy intake, this effect was observed together with increased levels of gut hormones peptide YY (PYY) and glucagon-like peptide-1 (GLP-1) secretion, which might indicated that propionate suppressed energy intake via stimulating gut hormone release that may tie in to brain pathways enhancing satiety and anorexia (Chambers et al., 2015).