MAPT and frontotemporal dementia: Over 50 different pathogenic MAPT missense, silent, and intronic mutations have been reported to be present in different sporadic tauopathies such as PSP, CBD, PiD, and FTLD-tau (frontotemporal dementia with parkinsonism caused by MAPT mutations; D’Souza et al., 1999; D’Souza and Schellenberg, 2005; Goedert et al., 2017; Strang et al., 2019).