IGF2BP2 and colorectal carcinoma: As expected, ectopic IMP2 expression significantly promoted the cell growth and colony formation ability of HCT116 and SW620 CRC cells, whereas IMP2 depletion suppressed the cell proliferative and colonic abilities of these two types of CRC cells (P < 0.05, Fig. 3b, c and Additional file 2: Fig. S3a, b).