FTO and colorectal carcinoma: For example, Qing et al. revealed that R-2-hydroxyglutarate attenuated aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis [5]; Liu et al. demonstrated that tumors could exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance [6]; Wang et al. indicated that LncRNA LINRIS promoted aerobic glycolysis by stabilizing IGF2BP2 in CRC [7].