The enzymatic activity of ARG1 in EVs from OvCa cell line supernatant or ascites of OvCa patients was higher than that of EVs isolated from benign cyst fluid, and research has demonstrated that ARG1+ EVs could inhibit CD4+ and CD8+ T cells in a dose-dependent manner in ovarian carcinoma [43]. Here, ARG1 is linked to ovarian carcinoma.