Additionally, ChIP-Seq data of AML cell lines and K562 cell line showed that the promoter region of EIF4EBP1 had coincident H3K27ac signals (Fig. 3h, tracks 1–6), while the ChIP-Seq data from K562 cells further indicated that EIF4EBP1 was bound by CEBPG at its TSS-proximal regions (Fig. 3h, track 7), suggesting a potential role for CEBPG in the transcriptional regulation of EIF4EBP1. Therefore, we next investigated the role of EIF4EBP1 in NB4 and K562 cells. This evidence concerns the gene EIF4EBP1 and acute myeloid leukemia.