VEGFA and melanoma: Using the list of prioritized genes with PoPS z scores >1, we performed enrichment analyses across Elsevier pathways,77 identifying Bonferroni-significant enrichment for VEGF/VEGFA/VEGF receptor/platelet-derived growth factor receptor/angiopoietin signaling, WNT signaling, endothelin signaling, atherosclerosis, arterial and pulmonary hypertension, melanoma, and proteins with altered expression in cancers (Figure 5A and 5B).