CASQ2 and breast cancer: Examination of the fibrillar collagen structures of the TME of xenograft tumors using second‐harmonic generation imaging [36] revealed no significant difference in the total amount of collagen (Fig. S8) but showed significantly increased frequency of straight‐angled collagen fibrillar structures in CASQ2‐overexpressing Hs578T tumors (Fig. 5D,E), which is an indicator of breast cancer invasiveness [37, 38, 39].