CD8A and neoplasm: The mean density of CD8+, in the tumor epithelium and tumor stroma compartments, was associated with OS (HR 1.003, CI 1.00–1.005, p = 0.020 and HR 0.996, CI 0.992–1.000, p = 0.039, respectively; supplementary material, Table S8), as well as with the combined mean density (p = 0.004 and p = 0.009, Table 2).