LGALS1 and type 2 diabetes mellitus: We observed no significant effect of genetically elevated levels of galectin-1 on odds of type 2 diabetes using either the sentinel SNP (Wald ratio OR 1.05; 95% CI 0.98, 1.14; p = 0.19; Fig. 3a) or three variants within the LGALS1 locus (IVW OR 1.06; 95% CI 0.99, 1.14; p = 0.082) in DIAGRAM.