Furthermore, Megakaryoblastic leukemia 1 (MKL1), alternatively known as MRTF-A (myocardin-related transcription factor A), regulates endothelial-to-mesenchymal transition and oncogene-induced senescence during pathogenesis of hepatocellular carcinoma and other liver disorders [23, 24]. The gene discussed is MRTFA; the disease is hepatocellular carcinoma.