A poorer rate of patients' survival in pancreatic cancers expressing high levels of BAG3 protein and bag3 mRNA was previously reported,6 and here confirmed by a distinct analysis data set (p = .032) (Figure 3A); similar results were obtained analyzing bag3 expression in HNSCC, where patients with low bag3 expression showed longer overall survival if compared to patients with higher BAG3 expression (p = .034) (Figure 3B). This evidence concerns the gene BAG3 and head and neck squamous cell carcinoma.