Sorrentino et al. have found that depletion of pDCs with a specific antibody (m927) in a mouse model of Lewis lung carcinoma cell‐induced lung cancer reversed the immune‐suppressive microenvironment, including decreased tumor burden, activation of mDC and CD8+ T cells, and Th1‐ and Th17‐like cytokine production.35 The gene discussed is CD8A; the disease is neoplasm.