There was no significant difference in age, gender, red blood cell (RBC), hemoglobin (HB), platelet (PLT) count, alanine aminotransferase (ALT), aspartate aminotransferase (AST), TBIL, gamma-glutamyl transpeptidase (GGT), ALB, prothrombin time (PT), international normalized ratio (INR), ascites, hepatomegaly, splenomegaly, Child–Pugh scores and end-stage liver disease (MELD) scores between the TIPS group and the internal medicine group (Table 1). The gene discussed is ALB; the disease is End Stage Liver Disease.