PIK3R1 and breast carcinoma: For example: miR-29 can inhibit autophagy, and can maintain genomic stability by regulating the level of PIK3R1 in breast cancer [36, 37]; miR-96 can inhibit autophagy, and can promote the GIN by regulating the level of RAD51 in breast cancer [38, 39]; miR-182 can inhibit autophagy by regulating mTOR, and can enhance GIN by regulating BRCA1 in breast cancer [40, 41].