Of these 30 GOSC genes selected on the basis of involvement in satellite cell biology, only 4 are also included in the 116 myopathogenes, so known to cause muscular dystrophies/myopathies when mutated: these are PAX7, MEGF10, SELENON (formerly SEPN1) and CAPN3 (Fig. 2E). The gene discussed is MEGF10; the disease is muscular dystrophy.