Mutations in the sarcomeric component MYOPALLADIN (encoded by MYPN) causes several cardiomyopathies and a congenital form of slowly progressing nemaline myopathy with myofibre size variation and evident atrophy termed Nemaline Myopathy 11, Autosomal Recessive (NEM11; OMIM: 617336) [163]. The gene discussed is MYPN; the disease is nemaline myopathy.