Serum/glucocorticoid regulated kinase family member 3 (SGK3), a member of Aggrecan (AGC) protein kinase family member, acts as an oncogene in human cancers such as osteosarcoma (OS) [17], hepatocellular carcinoma (HCC) [18] and breast cancer [19]. Here, WEE1 is linked to hepatocellular carcinoma.