SGK3 and polycystic ovary syndrome: The data indicated that miR-182 and SGK3-WT co-transfection resulted in an obvious suppression, and in-miR-182 and SGK3-WT co-transfection led to a significant enhancement in the luciferase activity in PCOS GCs and KGN cells; however, the luciferase activity was not changed in SGK3-MUT group (Fig. 4B and C).