Although neoadjuvant chemotherapy had no effect on the mesenchymal cell subset composition or PD-L1 expression compared to non-treated patients (data not shown), treatment of CD90+CD73+ mesenchymal subset with conventional chemotherapy using cisplatin/pemetrexed did not result in a significant increase in Annexin V/PI staining (% 0.8±0.3) compared with NSCLC cell lines (% 13.1±8) (Fig. 4e). Here, ANXA5 is linked to non-small cell lung carcinoma.