lncRNA-LUADT1 competitively binds miR-1207-5p to regulate TEAD1, activates Hippo/YAP signaling pathway, and promotes proliferation, migration, and invasion of NPC cell lines, thereby aggravating NPC development, suggesting that lncRNA-LUADT1/miR-1207-5p/TEAD1 can be used as the target of NPC, providing innovative concepts for early disease diagnosis and treatment. The gene discussed is YAP1; the disease is nasopharyngeal carcinoma.