Correspondingly, PELI1 knockdown specifically promoted the expression of the Bcl‐XL protein in IR‐treated TE‐1, ECA‐109, SCC‐9 and SiHa squamous carcinoma cells (Fig. 6I, Fig. S5A), while overexpression of PELI1 also reduced the Bcl‐XL protein levels in these tumor cells (Fig. 6J, Fig. S5B). This evidence concerns the gene PELI1 and squamous cell carcinoma.