For example, sclerostin levels were reported to be higher in 40 T2DM patients compared with age‐matched controls,(14) consistent with the recognized relationship between T2DM and fracture risk .15, 16, 17 Sclerostin levels have also been found to be increased in CKD patients, reflecting an inverse relationship between glomerular filtration rate (GFR) and sclerostin levels, which is not explained by reduced renal elimination.(18). Here, SOST is linked to type 2 diabetes mellitus.