{TBL 5} In addition, sclerostin was positively associated with severity of coronary artery disease on angiogram at study entry, as reflected by Friesinger score (0.05; 0.01, 0.09); there was also evidence that sclerostin was associated with an increased risk of coronary artery stenosis (1.16; 1.02, 1.32). The gene discussed is SOST; the disease is coronary artery disorder.