SOX11 and mantle cell lymphoma: To further investigate the effect of SAMHD1 on expression of SOX11 we depleted SAMHD1 in MCL cell lines (Granta-519, JeKo-1 and JVM-2) by means of non-infectious virus-like particles (VLPs), including Vpx that targets SAMHD1 protein for ubiquitin-mediated proteolysis within three hours and dX that serves as a control [18].