Vasospasm alone is thought to account for an 80% loss in perfusion after SCI.4 Vasospasm results in spinal cord ischemia (step 2) as we have previously shown.31 In step 3, ischemia is known to induce luminal uptake of glucose by the sodium glucose cotransporter (SGLT) and glucose transporter 1 (GLUT1) at the blood–brain barrier.24 Thus, contusion-induced ischemia would be expected to trigger glucose uptake into the injured spinal cord through SGLT or GLUT1, resulting in hyperglucoses. This evidence concerns the gene SLC2A1 and spinal cord ischemia.