Figure 1B and Supplementary Figure S3A indicate that the expression of OSBPL3 is significantly upregulated in all types of cancers except only kidney renal clear cell carcinoma (KICH). The results of the CPTAC dataset also showed similar results in cancer types of renal, colon, and lung cancers and uterine corpus endometrial carcinoma (Supplementary Figure S3B, p < 0.001). The gene discussed is OSBPL3; the disease is cancer.