Figure 12A shows the interaction network of top 20 OSBPL3-binding proteins, and Figure 12B shows the top six of the top 100 positively correlated genes with the OSBPL3 expression level—ANKLE2 (R = 0.44), BIRC6, LRIG2, TMEM170A, ZNF490, and C1GLAT1 genes (all p < 0.001). Similar results were found in the majority of cancers by a corresponding heatmap (Figure 12C). An intersection analysis of the above two groups reached one common member, namely, CRN1 (Figure 12D). This evidence concerns the gene OSBPL3 and cancer.