The membrane penetrating AMPs have broad application prospects, the previous researches found their usage as food preservatives (Chikindas et al., 2018; Aymerich et al., 2019), the antimicrobial surgical dressing products to prevent wound infections (Lin et al., 2019; Chen et al., 2021), and even developed into a novel preparation like hydrogel for the prophylaxis of bacterial vaginosis (Aymerich et al., 2019). The gene discussed is ADSL; the disease is bacterial vaginosis.