The mechanism of visceral fat loss in cancer involves lipolysis by stimulation of the hormone-sensitive lipase and adipose tissue triglyceride lipase which is mediated by cytokines and other lipolytic factors as for instance zinc alpha2-glycoprotein (Bing, 2011; Das et al., 2011). No study has been performed on the link between fat wasting and microbiota in cancer. Here, DDHD2 is linked to cancer.