Similarly, Clinical Proteomic Tumor Analysis Consortium (CPTAC) big data analysis [website http://ualcan.path.uab.edu/index.html (33)] indicates that high mRNA levels of cyclin D1 and LEF-1 in CRC tumor parts compared to non-tumor specimens (Supplementary Figures 8A, B). Here, LEF1 is linked to colorectal carcinoma.