CCNA2 and esophageal squamous cell carcinoma: To confirm whether CDCA7 promotes cell cycle through CCNA2, we carried out the interference and rescue experiment of CCNA2. The results showed that forced overexpression of CCNA2 in CDCA7 knockdown ESCC cells (Figure 6A) was performed, and a series of phenotype changes had been identified in ESCC cells.