We found that the results of GO, KEGG and GSEA function enrichment were significantly enriched in biological processes and pathways such as cell junction assembly, skin barrier, cytoskeleton, epidermal differentiation, lymphocyte migration, regulation of lymphocyte chemotaxis, mTORC1 signaling pathway and PI3K-Akt signaling pathway, and ultimately pointed to the direction of tumor immunity and tumor metastasis. The gene discussed is AKT1; the disease is neoplasm.