CYP3A4 and hepatocellular carcinoma: To verify the prognosis-related genes (ASPM, AURKA, CDC20, CDCA5, KIFC1, NCAPG, PRC1, PTTG1, TOP2A, and CYP3A4) in HCC, the expression analysis between tumor and normal samples were presented, where we observed that the mRNA expressions of all the genes except for CYP3A4 were significantly upregulated, while CYP3A4 presented the opposite trend (Figure 6).