◊ UC patients: ↑ colonic IL-33 mRNA levels and activated eosinophils (100)◊ IBD patients’ intestinal biopsies (101–103): - ST2/IL-33 signaling - Eosinophil infiltration which coincided with Th2 mediated immune response - IL-4, IL-5 and IL-13 release. The gene discussed is IL33; the disease is inflammatory bowel disease.