showed that high expression of CXCL12 was observed in malignant human ovarian epithelial tumor cells, and CXCL12 induced adhesion, transmigration and chemotaxis of pDCs, and inhibited tumor macrophage IL-10-induced pDC apoptosis through CXCR4, resulting in poorly proliferating T cells (13). This evidence concerns the gene CXCR4 and neoplasm.