CHRNA5 and Nasal polyposis: First, we analyzed samples of nasal polyps from 123 non-smoking patients with the three CHRNA5 genotypes at position 78590583 on GRCh38: wild-type (WT, G/G), heterozygous (HT, G/A), and homozygous (HO, A/A) for rs16969968 (α5SNP).