In addition, the normal HSC compartment CD34+ CD38- CD19- was unaffected as it is of normal size and does not contain the fusion protein and could generate multilineage reconstitution The t(9;22)(q34;q11) is commonly associated to CML but it can also lead to ALL. The gene discussed is CD34; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.