The BAZ1A gene within the 14q12-q13 amplicon is frequently amplified in esophageal squamous cell carcinoma (ESCC), while this region harbors some oncogenic genes whose amplification leads to the development and progression of various types of tumors, such as small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) [27]. The gene discussed is BAZ1A; the disease is non-small cell lung carcinoma.