NUP98 and acute megakaryoblastic leukemia: Moreover, a NUP98-BPTF gene fusion in which a C-terminal chromatin recognition module of BPTF is fused to the N-terminal moiety of NUP98 has been identified in primary refractory acute megakaryoblastic leukemia (AMKL) that contributes to refining the NUP98 rearrangement subgroup of pediatric AMKL [98].