According to data provided by the FSH Society, we were able to compare a total of 23 FSHD registries located in 5 continents (4 in Asia, 1 in Africa, 4 in America, 11 in Europe and 3 in Oceania) [27–32] which were collectively analyzed based on patient’s number within and on specific features as reported in Fig. 3 and in Additional file 2. The gene discussed is BRD2; the disease is Facioscapulohumeral dystrophy.