The result of this trial is expected to confirm that the new type of acupressure wrist-ankle strap can significantly improve the sleep quality and anxiety disorder of patients, reduce the suffering of patients, and improve the quality of life; it can also shorten the latency to fall asleep, increase the total sleep time, reduce the number of arousals and duration, improve sleep efficiency; it can reduce ACTH, CORT, 5-HT, and NA in the peripheral blood of patients with insomnia, thereby improving sleep quality. This evidence concerns the gene POMC and insomnia measurement.