Lo et al. have reported that the densities of CD3 + T cells, CD8 + T cells and PD-1 + T cells increased in HGSOC after chemotherapy of platinum, and the increase of these T cell subtypes was associated with the presence of immunocytes before treatment, which suggested that platinum chemotherapy could induce expected immune reaction if the necessary immunocytes had already been in the tumor [49]. The gene discussed is CD8A; the disease is neoplasm.