Compared with the paracancerous tissues, the expression of CXCL13(P = 0.0093), IDO1(P = 0.0068), PI3(P = 0.0161), SPP1(P = 0.0122) in tumor tissues was significantly increased, while TRIM22(P = 0.0342) was significantly decreased. The gene discussed is SPP1; the disease is neoplasm.