Vermunt Vermunt L L Sikkes Sikkes SAM SAM van den Hout van den Hout A A Duration of preclinical, prodromal, and dementia stages of Alzheimer’s disease in relation to age, sex, and APOE genotype Duration of preclinical, prodromal, and dementia stages of Alzheimer’s disease in relation to age, sex, and APOE genotype Alzheimers Dement Alzheimers Dement 2019 2019 15 15 888 888 898 898 10.1016/j.jalz.2019.04.001 10.1016/j.jalz.2019.04.001 31164314 31164314. The gene discussed is APOE; the disease is early-onset autosomal dominant Alzheimer disease.