Patients with BRAF V600E positive were similar to BRAF V600E negative patients in regards to lymph node metastases (57.1% vs 43.2%, P = 0.36), extra-thyroidal extension (34.1% vs 35.0%, P = 0.90), positive family history (8.8% vs 2.7%, respectively, P = 0.22), multifocality (44.0% vs 37.8%, P = 0.52), and the extent of neck dissection. Here, BRAF is linked to metastatic malignant neoplasm in the lymph nodes.