IL1B and congenital rubella syndrome: At present, the main view of studies hold that monocytes and macrophages are the main drivers of CRS, and the mechanism of them in CRS is as follows: after recognizing DAMP (damage‐associated molecular pattern) or PAMP (pathogen‐associated molecular pattern) moleculars by pattern recognition receptors (PRRs), they could produce inflammatory cytokines, such as IL‐1 and IL‐6, and thus participate in the occurrence and development of CRS.21