TNNI3 and obesity due to melanocortin 4 receptor deficiency: The left of Figure 1 lists mechanisms provoking release of cTnI and cTnT relevant to COVID-19 patients, especially the elderly, those with cardiovascular disease (CVD) including AMI, hypertension, arrythmia, demand ischemia including coronary disease, pro-thrombotic and pro-thrombosis events, and ARDS, obesity including hyperlipidemia and diabetes, and presence of pro-inflammatory cytokines.