SNHG1, which is upregulated in both osteosarcoma tissues and cells, is reported to be correlated with worse OS of osteosarcoma patients and can facilitate cell proliferation, migration and invasion via the miR-101-3p/ROCK1 axis, the miR-326/NOB1 axis, and the miR-577/WNT2B/Wnt/β-catenin axis, respectively (Jiang et al., 2018; Wang et al., 2018; Deng et al., 2019). The gene discussed is ROCK1; the disease is osteosarcoma.